Jasper KAMPHUIS - Admis au titre de docteur

jbj.kamphuis@gmail.com
jasper.kamphuis@inserm.fr
Identifiant ORCID 000000028494613X
Identifiant Hal https://hal.archives-ouvertes.fr/search/index/?q=%2A&authIdHal_s=jbj-kamphuis
Compte LinkedIn https://www.linkedin.com/in/jbjkamphuis/
Compte Researchgate https://www.researchgate.net/profile/Jasper_Kamphuis

Doctorat

Thèse soutenue le 4 octobre 2019 - Institut National Polytechnique de Toulouse

Ecole doctorale : SEVAB - Sciences Ecologiques, Vétérinaires, Agronomiques et Bioingenieries

Sujet : Une consommation accrue de carbohydrates fermentescibles entraîne des symptômes de type SII ; vers une meilleure compréhension des mécanismes impliqués

Mots-clés de la thèse : sensibilité viscérale,barrière intestinale,FODMAPs,mucus intestinale,mastocytes,glycation

Direction de thèse : Hélène EUTAMENE

Co-direction de thèse : Vassilia THEODOROU

Unité de recherche : TOXALIM - Laboratoire de Toxicologie Alimentaire UMR 1331 - Toulouse
Intitulé de l'équipe : NGN - Neurogastroentérologie et Nutrition

Master Européen - Biology, Master of Science

obtenu en juin 2014 - Wageningen University
Option : Molecular Development and Gene Regulation

Production scientifique

- William P. M. Worrall*, Jasper B. J. Kamphuis*, Julien Stackowicz,Aurélie Mougel,Emilie Mauré,Cyprien Pecalvel,Sébastien Brûlé,Pierre Bruhns,Laurent Guilleminault,Laurent L. Reber 2022. Anti-FcεRI antibody MAR-1 depletes basophils and cross-reacts with myeloid cells through its Fc portion Allergy, 00:1–4., https://doi.org/10.1111/all.15269
- Kamphuis, Jasper B.J.; Reber, Laurent L.; Eutamene, Helene; Theodorou, Vassilia 2022. Increased fermentable carbohydrate intake alters colonic mucus barrier function through glycation processes and increased mast cell counts FASEB journal, 36 (5); e22297, https://doi.org/10.1096/fj.202100494RRR
- Kamphuis, Jasper B. J. Worrall, William P. M. Stackowicz, Julien Mougel, Aurélie Mauré, Emilie Conde, Eva Bruhns, Pierre Guilleminault, Laurent Gaudenzio, Nicolas Chen, Jinmiao Gentek, Rebecca Reber, Laurent L. 2021. “Comment on “Tumor-initiating cells establish an IL-33–TGF-β niche signaling loop to promote cancer progression” Science, 372: 6538, https://doi.org/10.1126/science.abf2022
- Jasper B.J. Kamphuis, Bruno Guiard, Mathilde Leveque, Maiwenn Olier, Isabelle Jouanin, Sophie Yvon, Valerie ondereau, Pauline Rivière, Françoise Guéraud, Sylvie Chevolleau, Maria-Helena Noguer-Meireles, Jean- François Martin, Laurent Debrauwer, Helene Eutamène, Vassilia Theodorou 2019. Lactose and Fructo-oligosaccharides Increase Visceral Sensitivity in Mice via Glycation Processes, Increasing Mast Cell Density in Colonic Mucosa Gastroenterology, Volume 158, Issue 3, February 2020, Pages 652-663.e6, https://www.gastrojournal.org/article/S0016-5085(19)41528-X/fulltext
- J. Kamphuis (Toulouse), B. Guiard (Toulouse), P. Rivière (Bordeaux), S. Yvon (Toulouse), V. Tondereau (Toulouse), H. Eutamène (Toulouse), V. Theodorou (Toulouse) 2018. CO-23 L’administration de FODMAPS de type fructo-oligosaccharides (FOS) augmente la sensibilité abdominale et le nombre de mastocytes muqueux via la production d’agents de glycation par le microbiote intestinal JFHOD 2018, Jeudi 22 mars 2018 08:30 - 10:15; 8:42, https://www.snfge.org/content/ladministration-de-fodmaps-de-type-fructo-oligosaccharides-fos-augmente-la-sensibilite
- JBJ Kamphuis, S Yvon, V Tondereau, H Eutamène, V Theodorou 2018. Dietary FODMAPs can lead to microbial production of glycation agents, increasing mucosal mastocytes and impacting colonic mucus barrier function. UEGW 2018 Vienne, Autriche, P1868, https://www.ueg.eu/fileadmin/user_upload/documents/week2018/UEGWeek2018.AbstractBook.pdf
- J.B.J. Kamphuis, B. Guiard, S. Yvon, P. Riviere, V. Tondereau, H. Eutamene, V. Theodorou 2018. Dietary FODMAPs such as Fructooligosaccharides and lactose can increase abdominal sensitivity and the number of mastocytes in mice; a study on underlying mechanisms UEGW 2018 Vienne, Autriche, P1688, https://www.ueg.eu/fileadmin/user_upload/documents/week2018/UEGWeek2018.AbstractBook.pdf
- Pauline Talbot, Joanna M. Radziwill-Bienkowska, Jasper B.J. Kamphuis, Karine Steenkeste, Sarah Bettini, Véronique Robert, Marie-Louise Noordine, Camille Mayeur, Eric Gaultier, Philippe Langella, Catherine Robbe-Masselot, Eric Houdeau, Muriel Thomas, Muriel Mercier-Bonin 2018. Food-grade TiO2 is trapped by intestinal mucus in vitro but does not impair mucin O-glycosylation and short-chain fatty acid synthesis in vivo: implications for gut barrier protection Journal of Nanobiotechnology, 16:53, https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0379-5
- Jasper Kamphuis, Bruno Guiard, Pauline Rivière, Sophie Yvon, Valerie Tondereau, Helene Eutamene, Vassilia Theodorou 2018. Sa1596 - Dietary Fodmaps Such as Fructo-Oligosaccharides can Increase Abdominal Sensitivity and the Number of Mucosal Mastocytes in Mice Through Production of Glycating Agents by the Intestinal Microbiota Gastroenterology, 154(6):S-325, https://doi.org/10.1016/S0016-5085(18)31420-3
- J. Kamphuis, B. Guiard, P. Rivière, S. Yvon, V. Tondereau, H. Eutamène,V. Theodorou 2018. The effects of a diet rich in fructo- oligosaccharides on abdominal sensitivity: A study on underlying mechanisms of action FNM 2018 Amsterdam, 183, https://onlinelibrary.wiley.com/doi/epdf/10.1111/nmo.13423
- Joanna Radziwill-Bienkowska, Pauline Talbot, Jasper Kamphuis, Veronique Robert, Christel Cartier, Isabelle Fourquaux, Esther Lentzen, Jean-Nicolas Audinot, Frédéric Jamme, Matthieu Réfrégiers, Jacek Bardowski, Philippe Langella, Magdalena Kowalczyk, Eric Houdeau, Muriel Thomas, Muriel Mercier-Bonin 2018. Toxicity of Food-Grade TiO2 to Commensal Intestinal and Transient Food-Borne Bacteria: New Insights Using Nano-SIMS and Synchrotron UV Fluorescence Imaging Frontiers in Microbiology, 9:794, https://www.frontiersin.org/articles/10.3389/fmicb.2018.00794/full
- JBJ Kamphuis, M Mercier-Bonin, H Eutamene, V Theodorou 2017. CO110 - Colonic load differentiates organization of mucus in colon of mouse and rat; a remodelling CECED SNFGE, Abstract JFHOD 2017, https://www.snfge.org/content/colonic-load-differentiates-organization-muc
- Kamphuis Jasper, Rivière Pauline, Yvon Sophie, Tondereau Valerie, Eutamène Hélène, Theodorou Vassilia 2017. CO55 - Un régime enrichi en FODMAPs induit la production de métabolites toxiques par le microbiote intestinal, responsables d'une hypersensibilité viscérale. JFHOD - SNFGE, https://www.snfge.org/content/un-regime-enrichi-en-fodmaps-induit-la-producti, https://www.snfge.org/content/un-regime-enrichi-en-fodmaps-induit-la-producti
- Jasper B.J. Kamphuis, Muriel Mercier-Bonin, Helene Eutamene, Vassilia Theodorou 2017. Colonic Load Differentiates Organization of Mucus in Colon of Mouse and Rat; a Remodelling Gastroenterology, April 2017 Volume 152, Issue 5, Supplement 1, Page S505 , https://doi.org/10.1016/S0016-5085(17)31867-X
- Valérie Alquier- Bacquie, Valerie Bezirard, Jasper Kamphuis, Mathilde Leveque, Vassilia Theodorou, Laurent Ferrier 2017. Effects of GMO diets on the gut , pp.np,
- J.B.J. Kamphuis; M. Mercier-Bonin, H. Eutamene, V. Theodorou 2017. Mucus organisation is shaped by colonic content; a new view Scientific Reports, Scientific Reports 7:8527, https://www.nature.com/articles/s41598-017-08938-3
- J.B.J. Kamphuis, M. Mercier-Bonin, H. Eutamene, V. Theodorou 2017. Mucus organisation is shaped by colonic content; a new view. Mucins in Health and Disease (14th International Workshop on Carcinoma-Associated Mucins), 24 juillet 2017, https://www.kcl.ac.uk/lsm/research/divisions/cancer/research/groups/breastcancerbio/events/mucins
- Albusoda, A., Barki, N., Herregods, T., Kamphuis, J. B. J., Karunaratne, T. B., Lazarou, M., Lee, I., Mazurak, N., Perna, E., Polster, A., Pribic, T., Uhlig, F., Wang, H. and Enck, P. 2016. A fresh look at IBS—opportunities for systems medicine approaches Neurogastroenterology and Nutrition, Neurogastroenterol Motil, 29: n/a, e12989. doi:10.1111/nmo.12989, http://dx.doi.org/10.1111/nmo.12989
- Jasper Kamphuis, Pauline Riviere, Sophie Yvon, Valerie Tondereau, Hélène Eutamene, Vassilia Theodorou 2016. Effects of a high FODMAPS diet on visceral sensitivity: Involvement of advanced glycation end products and colonic mast cells Neurogastroenterology and Motility, 28:30-30 · August 2016, https://hal.archives-ouvertes.fr/hal-01602901
- Kamphuis Jasper, Yvon Sophie, Tondereau Valerie, Eutamène Hélène, Theodorou Vassilia 2016. P20 - Effets et mécanismes d’action d’un régime enrichi en lactose sur la sensibilité viscérale SNFGE-JFHOD, http://www.snfge.org/content/effets-et-mecanismes-daction-dun-regime-enric, http://www.snfge.org/content/effets-et-mecanismes-daction-dun-regime-enric
- Jasper Kamphuis, Pauline Rivière, Vassilia Theodorou, Hélène Eutamène 2016. “EFFECTS OF A HIGH FODMAPS DIET ON VISCERAL SENSITIVITY: INVOLVEMENT OF ADVANCED GLYCATION END PRODUCTS AND COLONIC MAST CELLS” GFNG Rouen, 23 Juin 2016, Rouen 9:30h Microbiota and nutrition in functional GI-diseases,

Dernière mise à jour le 18 mars 2025